Wuhan’s Jiangxia district is home to nearly 1 million residents.
The authorities took steps to ban large group events and dining at restaurants, close certain public entertainment venues and agricultural markets, and suspend bus and subway services for the next three days.
Authorities also urged residents not to leave the area during the three-day period and travelers to avoid entry.
The restrictions come after officials in the central city of 11 million people said they had detected two cases during regular mass testing and two more while screening close contact individuals.
Under China’s ultra-strict “COVID zero” policy, authorities across the country have imposed lockdowns and mass testing affecting millions of people in areas where even a handful of infections have been detected.
China claims to have one of the lowest COVID-19 death tolls in the world.
The world’s second-largest economy expanded just 0.4 percent year on year between April and June, official data showed on Friday, as lockdowns across the country stifled industrial production and consumer spending.
China has set an economic growth target of about 5.5 percent for 2022, which economists widely believe Beijing will struggle to reach under Beijing’s harsh pandemic rules.
In December 2019, the first Covid-19 virus was reported from Wuhan, China.